| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NUCB2 |
| Gene ID: | 4925 |
| Uniprot ID: | NUCB2_HUMAN |
| Immunogen Region: | 321-420 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 321-420 of human NUCB2 (NP_005004.1). |
| Immunogen Sequence: | ATEKKEFLEPDSWETLDQQQ FFTEEELKEYENIIALQENE LKKKADELQKQKEELQRQHD QLEAQKLEYHQVIQQMEQKK LQQGIPPSGPAGELKFEPHI |
| Tissue Specificity | Predominantly expressed in spleen, testis and normal stomach. |
| Function | Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. |
| Protein Name | Nucleobindin-2 Dna-Binding Protein Nefa Epididymis Secretory Protein Li 109 Gastric Cancer Antigen Zg4 Prepronesfatin Cleaved Into - Nesfatin-1 |
| Cellular Localisation | Golgi Apparatus Membrane Peripheral Membrane Protein Cytoplasm Secreted Endoplasmic Reticulum Nucleus Envelope Golgi Retention Is Mediated By Its N-Terminal Region Nesfatin-1: Secreted |
| Alternative Antibody Names | Anti-Nucleobindin-2 antibody Anti-Dna-Binding Protein Nefa antibody Anti-Epididymis Secretory Protein Li 109 antibody Anti-Gastric Cancer Antigen Zg4 antibody Anti-Prepronesfatin Cleaved Into - Nesfatin-1 antibody Anti-NUCB2 antibody Anti-NEFA antibody |
Information sourced from Uniprot.org