Anti-NTRK3 antibody (281-330 aa) (STJ96530)

SKU:
STJ96530
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-NT-3 growth factor receptor (281-330 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
ELISA 1:20000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:NTRK3
Gene ID:4916
Uniprot ID:NTRK3_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human NTRK3 at the amino acid range 281-330
Immunogen Region:281-330 aa
Specificity:Trk C Polyclonal Antibody detects endogenous levels of Trk C protein.
Post Translational Modifications Ligand-mediated auto-phosphorylation.
Function Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
Protein Name Nt-3 Growth Factor Receptor
Gp145-Trkc
Trk-C
Neurotrophic Tyrosine Kinase Receptor Type 3
Trkc Tyrosine Kinase
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-388844
Reactome: R-HSA-6811558
Reactome: R-HSA-9034013
Reactome: R-HSA-9034015
Reactome: R-HSA-9034793
Reactome: R-HSA-9034864
Reactome: R-HSA-9603381
Reactome: R-HSA-9603505
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Nt-3 Growth Factor Receptor antibody
Anti-Gp145-Trkc antibody
Anti-Trk-C antibody
Anti-Neurotrophic Tyrosine Kinase Receptor Type 3 antibody
Anti-Trkc Tyrosine Kinase antibody
Anti-NTRK3 antibody
Anti-TRKC antibody

Information sourced from Uniprot.org