| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-5 3 deoxyribonucleotidase, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NT5M |
| Gene ID: | 56953 |
| Uniprot ID: | NT5M_HUMAN |
| Specificity: | This antibody detects endogenous levels of NT5M at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human NT5M |
| Function | Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. |
| Protein Name | 5'(3'-Deoxyribonucleotidase - Mitochondrial5' -3'-Nucleotidase - MitochondrialDeoxy-5'-Nucleotidase 2Dnt-2 |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-5'(3'-Deoxyribonucleotidase - Mitochondrial antibodyAnti-5' -3'-Nucleotidase - Mitochondrial antibodyAnti-Deoxy-5'-Nucleotidase 2 antibodyAnti-Dnt-2 antibodyAnti-NT5M antibodyAnti-DNT2 antibody |
Information sourced from Uniprot.org
