Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-5 3 deoxyribonucleotidase, mitochondrial is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NT5M |
Gene ID: |
56953 |
Uniprot ID: |
NT5M_HUMAN |
Specificity: |
This antibody detects endogenous levels of NT5M at Human, Mouse |
Immunogen: |
Synthesized peptide derived from human NT5M |
Function | Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. |
Protein Name | 5'(3'-Deoxyribonucleotidase - Mitochondrial5' -3'-Nucleotidase - MitochondrialDeoxy-5'-Nucleotidase 2Dnt-2 |
Database Links | Reactome: R-HSA-73621 |
Cellular Localisation | Mitochondrion |
Alternative Antibody Names | Anti-5'(3'-Deoxyribonucleotidase - Mitochondrial antibodyAnti-5' -3'-Nucleotidase - Mitochondrial antibodyAnti-Deoxy-5'-Nucleotidase 2 antibodyAnti-Dnt-2 antibodyAnti-NT5M antibodyAnti-DNT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance