| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-5 3 deoxyribonucleotidase, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NT5M |
| Gene ID: |
56953 |
| Uniprot ID: |
NT5M_HUMAN |
| Specificity: |
This antibody detects endogenous levels of NT5M at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human NT5M |
| Function | Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. |
| Protein Name | 5'(3'-Deoxyribonucleotidase - Mitochondrial5' -3'-Nucleotidase - MitochondrialDeoxy-5'-Nucleotidase 2Dnt-2 |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-5'(3'-Deoxyribonucleotidase - Mitochondrial antibodyAnti-5' -3'-Nucleotidase - Mitochondrial antibodyAnti-Deoxy-5'-Nucleotidase 2 antibodyAnti-Dnt-2 antibodyAnti-NT5M antibodyAnti-DNT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
