Anti-NT5C2 antibody (STJ190738)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Cytosolic purine 5 nucleotidase for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NT5C2 |
| Gene ID | 22978 |
| Uniprot ID | 5NTC_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | 5NTC Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell. |
| Protein Name | Cytosolic Purine 5'-NucleotidaseCytosolic 5'-Nucleotidase IiCn-IiCytosolic Imp/Gmp-Specific 5'-NucleotidaseCytosolic Nucleoside Phosphotransferase 5'NHigh Km 5'-Nucleotidase |
| Database Links | Reactome: R-HSA-2161541Reactome: R-HSA-74259Reactome: R-HSA-9755088 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Cytosolic Purine 5'-Nucleotidase antibodyAnti-Cytosolic 5'-Nucleotidase Ii antibodyAnti-Cn-Ii antibodyAnti-Cytosolic Imp/Gmp-Specific 5'-Nucleotidase antibodyAnti-Cytosolic Nucleoside Phosphotransferase 5'N antibodyAnti-High Km 5'-Nucleotidase antibodyAnti-NT5C2 antibodyAnti-NT5B antibodyAnti-NT5CP antibodyAnti-PNT5 antibody |
Information sourced from Uniprot.org