| Short Description : | Rabbit polyclonal anti-28S rRNA-methyltransferase (320-400 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NSUN5 |
| Gene ID: | 55695 |
| Uniprot ID: | NSUN5_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 320-400 |
| Immunogen Region: | 320-400 aa |
| Specificity: | NSUN5 Polyclonal Antibody detects endogenous levels of protein. |
| Function | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development. |
| Protein Name | 28s RrnaCytosine-C(5-MethyltransferaseNol1-Related ProteinNol1rNol1/Nop2/Sun Domain Family Member 5Williams-Beuren Syndrome Chromosomal Region 20a Protein |
| Database Links | |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-28s Rrna antibodyAnti-Cytosine-C(5-Methyltransferase antibodyAnti-Nol1-Related Protein antibodyAnti-Nol1r antibodyAnti-Nol1/Nop2/Sun Domain Family Member 5 antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 20a Protein antibodyAnti-NSUN5 antibodyAnti-NSUN5A antibodyAnti-WBSCR20 antibodyAnti-WBSCR20A antibody |
Information sourced from Uniprot.org
