Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Monoclonal |
Clone ID : | S4204RM |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | NSDHL |
Gene ID: | 50814 |
Uniprot ID: | NSDHL_HUMAN |
Immunogen Region: | 50-150 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human NSDHL (NP_057006.1). |
Immunogen Sequence: | GQHMVEQLLARGYAVNVFDI QQGFDNPQVRFFLGDLCSRQ DLYPALKGVNTVFHCASPPP SSNNKELFYRVNYIGTKNVI ETCKEAGVQKLILTSSASVI F |
Tissue Specificity | Brain, heart, liver, lung, kidney, skin and placenta. |
Function | Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis. Also plays a role in the regulation of the endocytic trafficking of EGFR. |
Protein Name | Sterol-4-Alpha-Carboxylate 3-Dehydrogenase - Decarboxylating Protein H105e3 |
Database Links | Reactome: R-HSA-191273 |
Cellular Localisation | Endoplasmic Reticulum Membrane Single-Pass Membrane Protein Lipid Droplet Trafficking Through The Golgi Is Necessary For Er Membrane Localization |
Alternative Antibody Names | Anti-Sterol-4-Alpha-Carboxylate 3-Dehydrogenase - Decarboxylating antibody Anti-Protein H105e3 antibody Anti-NSDHL antibody Anti-H105E3 antibody |
Information sourced from Uniprot.org