| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Sterol-4-Alpha-Carboxylate 3-Dehydrogenase-Decarboxylating (50-150) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4204RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NSDHL |
| Gene ID: |
50814 |
| Uniprot ID: |
NSDHL_HUMAN |
| Immunogen Region: |
50-150 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human NSDHL (NP_057006.1). |
| Immunogen Sequence: |
GQHMVEQLLARGYAVNVFDI QQGFDNPQVRFFLGDLCSRQ DLYPALKGVNTVFHCASPPP SSNNKELFYRVNYIGTKNVI ETCKEAGVQKLILTSSASVI F |
| Tissue Specificity | Brain, heart, liver, lung, kidney, skin and placenta. |
| Function | Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis. Also plays a role in the regulation of the endocytic trafficking of EGFR. |
| Protein Name | Sterol-4-Alpha-Carboxylate 3-Dehydrogenase - DecarboxylatingProtein H105e3 |
| Database Links | Reactome: R-HSA-191273 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLipid DropletTrafficking Through The Golgi Is Necessary For Er Membrane Localization |
| Alternative Antibody Names | Anti-Sterol-4-Alpha-Carboxylate 3-Dehydrogenase - Decarboxylating antibodyAnti-Protein H105e3 antibodyAnti-NSDHL antibodyAnti-H105E3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunofluorescence analysis of U-2 OS cells using [KO Validated] NSDHL Rabbit polyclonal antibody (STJ119221) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98093/381689/STJ119221_1__50370.1713149871.jpg?c=1 "Immunofluorescence analysis of U-2 OS cells using [KO Validated] NSDHL Rabbit polyclonal antibody (STJ119221) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
