| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-NSD3 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S0MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NSD3 |
| Gene ID: |
54904 |
| Uniprot ID: |
NSD3_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NSD3/WHSC1L1 (Q9BZ95). |
| Immunogen Sequence: |
MDFSFSFMQGIMGNTIQQPP QLIDSANIRQEDAFDNNSDI AEDGGQTPYEATLQQGFQYP ATTEDLPPLTNGYPSSISVY ETQTKYQSYNQYPNGSANGF |
| Tissue Specificity | Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung. |
| Function | Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. |
| Protein Name | Histone-Lysine N-Methyltransferase Nsd3Nuclear Set Domain-Containing Protein 3Protein WhistleWhsc1-Like 1 Isoform 9 With Methyltransferase Activity To LysineWolf-Hirschhorn Syndrome Candidate 1-Like Protein 1Whsc1-Like Protein 1 |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Nsd3 antibodyAnti-Nuclear Set Domain-Containing Protein 3 antibodyAnti-Protein Whistle antibodyAnti-Whsc1-Like 1 Isoform 9 With Methyltransferase Activity To Lysine antibodyAnti-Wolf-Hirschhorn Syndrome Candidate 1-Like Protein 1 antibodyAnti-Whsc1-Like Protein 1 antibodyAnti-NSD3 antibodyAnti-WHSC1L1 antibodyAnti-DC28 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
