| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nardilysin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NRDC |
| Gene ID: |
4898 |
| Uniprot ID: |
NRDC_HUMAN |
| Specificity: |
This antibody detects endogenous levels of NRD1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human NRD1 |
| Function | Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs. Is a critical activator of BACE1- and ADAM17-mediated pro-neuregulin ectodomain shedding, involved in the positive regulation of axonal maturation and myelination. Required for proper functioning of 2-oxoglutarate dehydrogenase (OGDH). |
| Protein Name | NardilysinN-Arginine Dibasic ConvertaseNrd ConvertaseNrd-CNardilysin Convertase |
| Cellular Localisation | MitochondrionCell ProjectionDendrite |
| Alternative Antibody Names | Anti-Nardilysin antibodyAnti-N-Arginine Dibasic Convertase antibodyAnti-Nrd Convertase antibodyAnti-Nrd-C antibodyAnti-Nardilysin Convertase antibodyAnti-NRDC antibodyAnti-NRD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
