| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nurr1 (Internal Region) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS + 0.02% NaN3 |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:500-1:1000IHCICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NR4A2 |
| Gene ID: |
4929 |
| Uniprot ID: |
NR4A2_HUMAN |
| Immunogen Region: |
Internal Region |
| Specificity: |
Reacts with an internal sequence of the human Nurr1 protein. Also reacts with rat and mouse Nurr1. |
| Immunogen: |
Synthetic peptide corresponding to amino acids from an internal sequence of the human Nurr1 protein |
| Function | Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. |
| Protein Name | Nuclear Receptor Subfamily 4 Group A Member 2Immediate-Early Response Protein NotOrphan Nuclear Receptor Nurr1Transcriptionally-Inducible Nuclear Receptor |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-4090294 |
| Cellular Localisation | CytoplasmNucleusMostly NuclearOxidative Stress Promotes Cytoplasmic Localization |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 4 Group A Member 2 antibodyAnti-Immediate-Early Response Protein Not antibodyAnti-Orphan Nuclear Receptor Nurr1 antibodyAnti-Transcriptionally-Inducible Nuclear Receptor antibodyAnti-NR4A2 antibodyAnti-NOT antibodyAnti-NURR1 antibodyAnti-TINUR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
