Western blot analysis of lysates from Mouse brain, using (STJ119448) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Anti-NR4A2 antibody (90-170) (STJ119448)

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STJ119448
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NR4A2
Gene ID: 4929
Uniprot ID: NR4A2_HUMAN
Immunogen Region: 90-170
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 90-170 of human NR4A2 (NP_006177.1).
Immunogen Sequence: IKVEDIQMHNYQQHSHLPPQ SEEMMPHSGSVYYKPSSPPT PTTPGFQVQHSPMWDDPGSL HNFHQNYVATTHMIEQRKTP V
Tissue Specificity Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
Function Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
Protein Name Nuclear Receptor Subfamily 4 Group A Member 2
Immediate-Early Response Protein Not
Orphan Nuclear Receptor Nurr1
Transcriptionally-Inducible Nuclear Receptor
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-4090294
Cellular Localisation Cytoplasm
Nucleus
Mostly Nuclear
Oxidative Stress Promotes Cytoplasmic Localization
Alternative Antibody Names Anti-Nuclear Receptor Subfamily 4 Group A Member 2 antibody
Anti-Immediate-Early Response Protein Not antibody
Anti-Orphan Nuclear Receptor Nurr1 antibody
Anti-Transcriptionally-Inducible Nuclear Receptor antibody
Anti-NR4A2 antibody
Anti-NOT antibody
Anti-NURR1 antibody
Anti-TINUR antibody

Information sourced from Uniprot.org

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