Anti-NR2E1 antibody (STJ192313)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Nuclear receptor subfamily 2 group E member 1 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NR2E1 |
| Gene ID | 7101 |
| Uniprot ID | NR2E1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | NR2E1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acid receptor (RAR) regulation in retinal cells. |
| Protein Name | Nuclear Receptor Subfamily 2 Group E Member 1Nuclear Receptor TlxProtein Tailless HomologTllHtll |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-8943724 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 2 Group E Member 1 antibodyAnti-Nuclear Receptor Tlx antibodyAnti-Protein Tailless Homolog antibodyAnti-Tll antibodyAnti-Htll antibodyAnti-NR2E1 antibodyAnti-TLX antibody |
Information sourced from Uniprot.org