Name: Anti-NR2C1 antibody (40-120 aa) (STJ190193)
SKU: STJ190193
Availability: InStock

Anti-NR2C1 antibody (40-120 aa) (STJ190193)

SKU:

STJ190193

£49.00 - £261.00

Short Description :	Rabbit polyclonal anti-Nuclear receptor subfamily 2 group C member 1 (40-120 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:	WB/ELISA
Host:	Rabbit
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Polyclonal
Isotype:	IgG
Conjugation:	Unconjugated
Concentration:	1 mg/mL
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	NR2C1
Gene ID:	7181
Uniprot ID:	NR2C1_HUMAN
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 40-120
Immunogen Region:	40-120 aa
Specificity:	NR2C1 Polyclonal Antibody detects endogenous levels of protein.

Function	Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Protein Name	Nuclear Receptor Subfamily 2 Group C Member 1 Orphan Nuclear Receptor Tr2 Testicular Receptor 2
Database Links	Reactome: R-HSA-383280 Reactome: R-HSA-4090294
Cellular Localisation	Nucleus Pml Body Recruited By Hdac3 After All-Trans Retinoic Acid Stimulated Mapk1-Mediated Thr-223 Phosphorylation To Pml Bodies For Subsequent Sumoylation
Alternative Antibody Names	Anti-Nuclear Receptor Subfamily 2 Group C Member 1 antibody Anti-Orphan Nuclear Receptor Tr2 antibody Anti-Testicular Receptor 2 antibody Anti-NR2C1 antibody Anti-TR2 antibody

Information sourced from Uniprot.org

Anti-NR2C1 antibody (40-120 aa) (STJ190193)

General Information

Model	Name	Host	Clonality	Reactivity	Application
STJ190499	Anti-ACVR2B antibody (40-120 aa) (STJ190499)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/ELISA
STJ190356	Anti-KRT81 antibody (40-120 aa) (STJ190356)	Rabbit	Polyclonal	Human/Rat/Mouse	WB/ELISA
STJ190992	Anti-MEGF6 antibody (40-120 aa) (STJ190992)	Rabbit	Polyclonal	Human/Rat/Mouse	WB/ELISA
STJ190534	Anti-GALM antibody (40-120 aa) (STJ190534)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/ELISA
STJ191424	Anti-CCL23 antibody (40-120 aa) (STJ191424)	Rabbit	Polyclonal	Human/Rat/Mouse	WB/ELISA