Anti-NR1I3 antibody (71-120 aa) (STJ94035)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human NR1I3 at the amino acid range 71-120
STJ94035
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General Information

Short DescriptionRabbit polyclonal anti-Nuclear receptor subfamily 1 group I member 3 (71-120 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolNR1I3
Gene ID9970
Uniprot IDNR1I3_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human NR1I3 at the amino acid range 71-120
Immunogen Region71-120 aa
SpecificityMB67 Polyclonal Antibody detects endogenous levels of MB67 protein.

Additional Info

Post Translational Modifications Phosphorylated at Thr-38 by PKC, dephosphorylation of Thr-38 is required for nuclear translocation and activation.
Function Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Protein Name Nuclear Receptor Subfamily 1 Group I Member 3
Constitutive Activator Of Retinoid Response
Constitutive Active Response
Constitutive Androstane Receptor
Car
Orphan Nuclear Receptor Mb67
Database Links Reactome: R-HSA-383280
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Recruited To The Cytoplasm By Dnajc7
Alternative Antibody Names Anti-Nuclear Receptor Subfamily 1 Group I Member 3 antibody
Anti-Constitutive Activator Of Retinoid Response antibody
Anti-Constitutive Active Response antibody
Anti-Constitutive Androstane Receptor antibody
Anti-Car antibody
Anti-Orphan Nuclear Receptor Mb67 antibody
Anti-NR1I3 antibody
Anti-CAR antibody

Information sourced from Uniprot.org

Citations

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