| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-NPY6R (200-300 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Npy6r |
| Gene ID: | 18169 |
| Uniprot ID: | NPY6R_MOUSE |
| Immunogen Region: | 200-300 aa |
| Specificity: | Specific for NPY6R. |
| Immunogen: | A synthetic peptide from aa region of 200-300 of mouse NPY6R conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY = PYY >= NPY (2-36) = Leu-31, Pro-34 NPY > NPY (13-36) > PP. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity. |
| Protein Name | Neuropeptide Y Receptor Type 6Npy6-RPancreatic Polypeptide Receptor 2Pp2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Neuropeptide Y Receptor Type 6 antibodyAnti-Npy6-R antibodyAnti-Pancreatic Polypeptide Receptor 2 antibodyAnti-Pp2 antibodyAnti-Npy6r antibodyAnti-Npy5r antibodyAnti-Ppyr2 antibodyAnti-Y2b antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and CAT1 knockdown (KD) HeLa cells using [KD Validated] CAT1 Rabbit pAb (STJ11107042) at1:1000 dilution. <br>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. <br>Lysates/proteins: 17 Mu g per lane. <br>Blocking buffer: 3% nonfat dry milk in TBST. <br>Detection: ECL Basic Kit <br>Exposure time: 20s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/186238/407927/STJ11107042_1__86808.1744894391.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CAT1 knockdown (KD) HeLa cells using [KD Validated] CAT1 Rabbit pAb (STJ11107042) at1:1000 dilution. <br>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. <br>Lysates/proteins: 17 Mu g per lane. <br>Blocking buffer: 3% nonfat dry milk in TBST. <br>Detection: ECL Basic Kit <br>Exposure time: 20s.")
