• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NPTN Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-NPTN antibody (106-155) (STJ94440)

SKU:
STJ94440

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Neuroplastin (106-155) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NPTN
Gene ID: 27020
Uniprot ID: NPTN_HUMAN
Immunogen Region: 106-155
Specificity: Neuroplastin Polyclonal Antibody detects endogenous levels of Neuroplastin protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NPTN. AA range:106-155
Tissue Specificity Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level).
Function Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1.stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane.
Protein Name Neuroplastin
Stromal Cell-Derived Receptor 1
Sdr-1
Database Links Reactome: R-HSA-977443
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Postsynaptic Density
Alternative Antibody Names Anti-Neuroplastin antibody
Anti-Stromal Cell-Derived Receptor 1 antibody
Anti-Sdr-1 antibody
Anti-NPTN antibody
Anti-SDFR1 antibody
Anti-SDR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance