Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NPR3 (272-541) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NPR3 |
Gene ID: |
4883 |
Uniprot ID: |
ANPRC_HUMAN |
Immunogen Region: |
272-541 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 272-541 of human NPR3 (NP_001191304.1). |
Immunogen Sequence: |
LVAHRHGMTSGDYAFFNIEL FNSSSYGDGSWKRGDKHDFE AKQAYSSLQTVTLLRTVKPE FEKFSMEVKSSVEKQGLNME DYVNMFVEGFHDAILLYVLA LHEVLRAGYSKKDGGKIIQQ TWNRTFEGIAGQVSIDANGD RYGDFSVIAMTDVEAGTQEV IGDYFGKEGRFEMRPNVKYP WGPLKLRIDENRIVEHTNSS PCKSSGGLEESAVTGIVVGA LLGAGLLMAFYFFRKKYRI |
Function | Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. |
Protein Name | Atrial Natriuretic Peptide Receptor 3Atrial Natriuretic Peptide Clearance ReceptorAtrial Natriuretic Peptide Receptor Type CAnp-CAnpr-CNpr-C |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Atrial Natriuretic Peptide Receptor 3 antibodyAnti-Atrial Natriuretic Peptide Clearance Receptor antibodyAnti-Atrial Natriuretic Peptide Receptor Type C antibodyAnti-Anp-C antibodyAnti-Anpr-C antibodyAnti-Npr-C antibodyAnti-NPR3 antibodyAnti-ANPRC antibodyAnti-C5orf23 antibodyAnti-NPRC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance