| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NPR2 |
| Gene ID: | 4882 |
| Uniprot ID: | ANPRB_HUMAN |
| Immunogen Region: | 130-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-320 of human ANPRB/NRP2 (NP_003986.2). |
| Immunogen Sequence: | SAKNDHYRTLVRTGPSAPKL GEFVVTLHGHFNWTARAALL YLDARTDDRPHYFTIEGVFE ALQGSNLSVQHQVYAREPGG PEQATHFIRANGRIVYICGP LEMLHEILLQAQRENLTNGD YVFFYLDVFGESLRAGPTRA TGRPWQDNRTREQAQALREA FQTVLVITYREPPNPEYQEF QNRLLIRARED |
| Post Translational Modifications | Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated. |
| Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
| Protein Name | Atrial Natriuretic Peptide Receptor 2Atrial Natriuretic Peptide Receptor Type BAnp-BAnpr-BNpr-BGuanylate Cyclase BGc-B |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Atrial Natriuretic Peptide Receptor 2 antibodyAnti-Atrial Natriuretic Peptide Receptor Type B antibodyAnti-Anp-B antibodyAnti-Anpr-B antibodyAnti-Npr-B antibodyAnti-Guanylate Cyclase B antibodyAnti-Gc-B antibodyAnti-NPR2 antibodyAnti-ANPRB antibody |
Information sourced from Uniprot.org