• Western blot analysis of lysates from 293T cells, using ANPRB/NRP2 Rabbit polyclonal antibody (STJ118501) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-NPR2 antibody (130-320) (STJ118501)

SKU:
STJ118501

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NPR2 (130-320) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NPR2
Gene ID: 4882
Uniprot ID: ANPRB_HUMAN
Immunogen Region: 130-320
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-320 of human ANPRB/NRP2 (NP_003986.2).
Immunogen Sequence: SAKNDHYRTLVRTGPSAPKL GEFVVTLHGHFNWTARAALL YLDARTDDRPHYFTIEGVFE ALQGSNLSVQHQVYAREPGG PEQATHFIRANGRIVYICGP LEMLHEILLQAQRENLTNGD YVFFYLDVFGESLRAGPTRA TGRPWQDNRTREQAQALREA FQTVLVITYREPPNPEYQEF QNRLLIRARED
Post Translational Modifications Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated.
Function Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.
Protein Name Atrial Natriuretic Peptide Receptor 2
Atrial Natriuretic Peptide Receptor Type B
Anp-B
Anpr-B
Npr-B
Guanylate Cyclase B
Gc-B
Database Links Reactome: R-HSA-5578768
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Atrial Natriuretic Peptide Receptor 2 antibody
Anti-Atrial Natriuretic Peptide Receptor Type B antibody
Anti-Anp-B antibody
Anti-Anpr-B antibody
Anti-Npr-B antibody
Anti-Guanylate Cyclase B antibody
Anti-Gc-B antibody
Anti-NPR2 antibody
Anti-ANPRB antibody

Information sourced from Uniprot.org

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