Anti-NPR1/NPR-A antibody [SAA1818] (STJA0020246)

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STJA0020246
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Short Description :Human monoclonal Atrial Natriuretic Peptide Receptor 1 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA
Host:Human
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Clonality :Monoclonal
Clone ID :SAA1818
Isotype:IgG4
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Protein A/G purified from cell culture supernatant
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol:NPR1
Gene ID:4881
Uniprot ID:ANPRA_HUMAN
Function Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis.
Protein Name Atrial Natriuretic Peptide Receptor 1
Atrial Natriuretic Peptide Receptor Type A
Anp-A
Anpr-A
Npr-A
Guanylate Cyclase A
Gc-A
Database Links Reactome: R-HSA-5578768
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Atrial Natriuretic Peptide Receptor 1 antibody
Anti-Atrial Natriuretic Peptide Receptor Type A antibody
Anti-Anp-A antibody
Anti-Anpr-A antibody
Anti-Npr-A antibody
Anti-Guanylate Cyclase A antibody
Anti-Gc-A antibody
Anti-NPR1 antibody
Anti-ANPRA antibody

Information sourced from Uniprot.org

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