| Short Description : | Rabbit polyclonal anti-C-type natriuretic peptide for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NPPC |
| Gene ID: | 4880 |
| Uniprot ID: | ANFC_HUMAN |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Specificity: | ANFC Polyclonal Antibody detects endogenous levels of protein. |
| Post Translational Modifications | CNP-22: Degraded by IDE (in vitro). |
| Function | CNP-22: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Acts by specifically binding and stimulating NPR2 to produce cGMP. Binds the clearance receptor NPR3. |
| Protein Name | C-Type Natriuretic Peptide Cleaved Into - Cnp-22 - Cnp-29 - Cnp-53 |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Type Natriuretic Peptide Cleaved Into - Cnp-22 - Cnp-29 - Cnp-53 antibodyAnti-NPPC antibodyAnti-CNP2 antibody |
Information sourced from Uniprot.org
