Anti-NPAS1 antibody (445-494) (STJ94436)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human NPAS1. AA range:445-494
General Information
| Short Description | Rabbit polyclonal anti-Neuronal PAS domain-containing protein 1 (445-494) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NPAS1 |
| Gene ID | 4861 |
| Uniprot ID | NPAS1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NPAS1. AA range:445-494 |
| Immunogen Region | 445-494 |
| Specificity | Neuronal PAS1 Polyclonal Antibody detects endogenous levels of Neuronal PAS1 protein. |
Additional Info
| Function | May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level. Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH. |
| Protein Name | Neuronal Pas Domain-Containing Protein 1Neuronal Pas1Basic-Helix-Loop-Helix-Pas Protein Mop5Class E Basic Helix-Loop-Helix Protein 11Bhlhe11Member Of Pas Protein 5Pas Domain-Containing Protein 5 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Neuronal Pas Domain-Containing Protein 1 antibodyAnti-Neuronal Pas1 antibodyAnti-Basic-Helix-Loop-Helix-Pas Protein Mop5 antibodyAnti-Class E Basic Helix-Loop-Helix Protein 11 antibodyAnti-Bhlhe11 antibodyAnti-Member Of Pas Protein 5 antibodyAnti-Pas Domain-Containing Protein 5 antibodyAnti-NPAS1 antibodyAnti-BHLHE11 antibodyAnti-MOP5 antibodyAnti-PASD5 antibody |
Information sourced from Uniprot.org