| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Neuronal PAS domain-containing protein 1 (445-494) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NPAS1 |
| Gene ID: | 4861 |
| Uniprot ID: | NPAS1_HUMAN |
| Immunogen Region: | 445-494 |
| Specificity: | Neuronal PAS1 Polyclonal Antibody detects endogenous levels of Neuronal PAS1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NPAS1. AA range:445-494 |
| Function | May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level. Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH. |
| Protein Name | Neuronal Pas Domain-Containing Protein 1Neuronal Pas1Basic-Helix-Loop-Helix-Pas Protein Mop5Class E Basic Helix-Loop-Helix Protein 11Bhlhe11Member Of Pas Protein 5Pas Domain-Containing Protein 5 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Neuronal Pas Domain-Containing Protein 1 antibodyAnti-Neuronal Pas1 antibodyAnti-Basic-Helix-Loop-Helix-Pas Protein Mop5 antibodyAnti-Class E Basic Helix-Loop-Helix Protein 11 antibodyAnti-Bhlhe11 antibodyAnti-Member Of Pas Protein 5 antibodyAnti-Pas Domain-Containing Protein 5 antibodyAnti-NPAS1 antibodyAnti-BHLHE11 antibodyAnti-MOP5 antibodyAnti-PASD5 antibody |
Information sourced from Uniprot.org