| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-NADPH oxidase activator 1 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NOXA1 |
| Gene ID: | 10811 |
| Uniprot ID: | NOXA1_HUMAN |
| Specificity: | NOXA1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Interaction with YWHAZ depends on phosphorylation by PKA. |
| Function | Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. |
| Protein Name | Nadph Oxidase Activator 1Nox Activator 1Antigen Ny-Co-31Ncf2-Like ProteinP67phox-Like FactorP51-Nox |
| Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
| Cellular Localisation | CytoplasmCell MembraneTranslocation To Membranes Depends On Noxo1 Or Ncf1 And Maybe Rac1 |
| Alternative Antibody Names | Anti-Nadph Oxidase Activator 1 antibodyAnti-Nox Activator 1 antibodyAnti-Antigen Ny-Co-31 antibodyAnti-Ncf2-Like Protein antibodyAnti-P67phox-Like Factor antibodyAnti-P51-Nox antibodyAnti-NOXA1 antibodyAnti-P51NOX antibody |
Information sourced from Uniprot.org
