| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NOX3 |
| Gene ID: |
50508 |
| Uniprot ID: |
NOX3_HUMAN |
| Immunogen Region: |
223-395 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 223-395 of human NOX3 (NP_056533.1). |
| Immunogen Sequence: |
GRIVRGQTQDSLSLHNITFC RDRYAEWQTVAQCPVPQFSG KEPSAWKWILGPVVLYACER IIRFWRFQQEVVITKVVSHP SGVLELHMKKRGFKMAPGQY ILVQCPAISSLEWHPFTLTS APQEDFFSVHIRAAGDWTAA LLEAFGAEGQALQEPWSLPR LAVDGPFGTALTD |
| Post Translational Modifications | N-glycosylated in a CYBA/p22phox-dependent manner. |
| Function | NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor, upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. |
| Protein Name | Nadph Oxidase 3Mitogenic Oxidase 2Mox-2Gp91phox Homolog 3Gp91-3 |
| Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Nadph Oxidase 3 antibodyAnti-Mitogenic Oxidase 2 antibodyAnti-Mox-2 antibodyAnti-Gp91phox Homolog 3 antibodyAnti-Gp91-3 antibodyAnti-NOX3 antibodyAnti-MOX2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
