Anti-NOX1 antibody (418-564) (STJ113879)

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STJ113879
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:200-1:500
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NOX1
Gene ID: 27035
Uniprot ID: NOX1_HUMAN
Immunogen Region: 418-564
Specificity: A synthetic peptide corresponding to a sequence within amino acids 418-564 of human NOX1 (NP_008983.2?).
Immunogen Sequence: WYKFQCADHNLKTKKIYFYW ICRETGAFSWFNNLLTSLEQ EMEELGKVGFLNYRLFLTGW DSNIVGHAALNFDKATDIVT GLKQKTSFGRPMWDNEFSTI ATSHPKSVVGVFLCGPRTLA KSLRKCCHRYSSLDPRKVQF YFNKENF
Tissue Specificity Isoform NOH-1L: Detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes.
Post Translational Modifications Phosphorylation at Thr-430 mediated by PKC/PRKBC positively regulates its interaction with NOXA1 and enzyme activity.
Function NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. Isoform NOH-1L: NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor.
Protein Name Nadph Oxidase 1
Nox-1
Mitogenic Oxidase 1
Mox-1
Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox
Noh-1
Database Links Reactome: R-HSA-5668599
Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Reactome: R-HSA-9673324
Cellular Localisation Cell Projection
Invadopodium Membrane
Multi-Pass Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Nadph Oxidase 1 antibody
Anti-Nox-1 antibody
Anti-Mitogenic Oxidase 1 antibody
Anti-Mox-1 antibody
Anti-Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox antibody
Anti-Noh-1 antibody
Anti-NOX1 antibody
Anti-MOX1 antibody
Anti-NOH1 antibody

Information sourced from Uniprot.org