| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NOX1 (418-564) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:500IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NOX1 |
| Gene ID: |
27035 |
| Uniprot ID: |
NOX1_HUMAN |
| Immunogen Region: |
418-564 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 418-564 of human NOX1 (NP_008983.2?). |
| Immunogen Sequence: |
WYKFQCADHNLKTKKIYFYW ICRETGAFSWFNNLLTSLEQ EMEELGKVGFLNYRLFLTGW DSNIVGHAALNFDKATDIVT GLKQKTSFGRPMWDNEFSTI ATSHPKSVVGVFLCGPRTLA KSLRKCCHRYSSLDPRKVQF YFNKENF |
| Tissue Specificity | NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH-1S is detected only in colon and colon carcinoma cells. |
| Function | NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. |
| Protein Name | Nadph Oxidase 1Nox-1Mitogenic Oxidase 1Mox-1Nadh/Nadph Mitogenic Oxidase Subunit P65-MoxNoh-1 |
| Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
| Cellular Localisation | Cell ProjectionInvadopodium MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Nadph Oxidase 1 antibodyAnti-Nox-1 antibodyAnti-Mitogenic Oxidase 1 antibodyAnti-Mox-1 antibodyAnti-Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox antibodyAnti-Noh-1 antibodyAnti-NOX1 antibodyAnti-MOX1 antibodyAnti-NOH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
