| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-NADPH oxidase 1 (210-260 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:500-200 ELISA 1:10000-20000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NOX1 |
| Gene ID: | 27035 |
| Uniprot ID: | NOX1_HUMAN |
| Immunogen Region: | 210-260 aa |
| Specificity: | The antibody detects endogenous Mox1 |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 210-260 |
| Post Translational Modifications | Phosphorylation at Thr-430 mediated by PKC/PRKBC positively regulates its interaction with NOXA1 and enzyme activity. |
| Function | NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. Isoform NOH-1L: NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. |
| Protein Name | Nadph Oxidase 1 Nox-1 Mitogenic Oxidase 1 Mox-1 Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox Noh-1 |
| Database Links | Reactome: R-HSA-5668599 Reactome: R-HSA-9013149 Reactome: R-HSA-9013423 Reactome: R-HSA-9673324 |
| Cellular Localisation | Cell Projection Invadopodium Membrane Multi-Pass Membrane Protein Cell Membrane |
| Alternative Antibody Names | Anti-Nadph Oxidase 1 antibody Anti-Nox-1 antibody Anti-Mitogenic Oxidase 1 antibody Anti-Mox-1 antibody Anti-Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox antibody Anti-Noh-1 antibody Anti-NOX1 antibody Anti-MOX1 antibody Anti-NOH1 antibody |
Information sourced from Uniprot.org