| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NOP56 (1-160) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NOP56 |
| Gene ID: |
10528 |
| Uniprot ID: |
NOP56_HUMAN |
| Immunogen Region: |
1-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human NOP56 (NP_006383.2). |
| Immunogen Sequence: |
MVLLHVLFEHAVGYALLALK EVEEISLLQPQVEESVLNLG KFHSIVRLVAFCPFASSQVA LENANAVSEGVVHEDLRLLL ETHLPSKKKKVLLGVGDPKI GAAIQEELGYNCQTGGVIAE ILRGVRLHFHNLVKGLTDLS ACKAQLGLGHSYSRAKVKFN |
| Function | Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Nucleolar Protein 56Nucleolar Protein 5a |
| Database Links | Reactome: R-HSA-390471Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolusCytoplasmNucleoplasm |
| Alternative Antibody Names | Anti-Nucleolar Protein 56 antibodyAnti-Nucleolar Protein 5a antibodyAnti-NOP56 antibodyAnti-NOL5A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
