| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NOMO2 (873-1222) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NOMO2 |
| Gene ID: |
283820 |
| Uniprot ID: |
NOMO2_HUMAN |
| Immunogen Region: |
873-1222 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 873-1222 of human NOMO2 (NP_001004060.1). |
| Immunogen Sequence: |
YALAGVSFEIKAEDDQPLPG VLLSLSGGLFRSNLLTQDNG ILTFSNLSPGQYYFKPMMKE FRFEPSSQMIEVQEGQNLKI TITGYRTAYSCYGTVSSLNG EPEQGVAMEAVGQNDCSIYG EDTVTDEEGKFRLRGLLPGC VYHVQLKAEGNDHIERALPH HRVIEVGNNDIDDVNIIVFR QINQFDLSGNVITSSEYLPT LWVKLYKSENLDNPIQTVSL GQSLFFHFPPLLRDGENYV |
| Tissue Specificity | Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart. |
| Function | Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions. |
| Protein Name | Bos Complex Subunit Nomo2Nodal Modulator 2Pm5 Protein 2 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Bos Complex Subunit Nomo2 antibodyAnti-Nodal Modulator 2 antibodyAnti-Pm5 Protein 2 antibodyAnti-NOMO2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
