| Short Description : | Rabbit polyclonal NOL6 (1032-1146) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NOL6 |
| Gene ID: | 65083 |
| Uniprot ID: | NOL6_HUMAN |
| Immunogen Region: | 1032-1146 |
| Immunogen Sequence: | SFCRGLLSQPGPSSLMPVLG YDPPQLYLTQLREAFGDLAL FFYDQHGGEVIGVLWKPTSF QPQPFKASSTKGRMVMSRGG ELVMVPNVEAILEDFAVLGE GLVQTVEARSERWTV |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1032-1146 of human NOL6 (NP_075068.2). |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Nucleolar Protein 6Nucleolar Rna-Associated ProteinNrap |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolusChromosomeLocalizes To Condensed Chromosomes In Mitosis |
| Alternative Antibody Names | Anti-Nucleolar Protein 6 antibodyAnti-Nucleolar Rna-Associated Protein antibodyAnti-Nrap antibodyAnti-NOL6 antibody |
Information sourced from Uniprot.org
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