| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NNT (881-1086) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NNT |
| Gene ID: |
23530 |
| Uniprot ID: |
NNTM_HUMAN |
| Immunogen Region: |
881-1086 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 881-1086 of human NNT (NP_036475.3). |
| Immunogen Sequence: |
NRSLANVILGGYGTTSTAGG KPMEISGTHTEINLDNAIDM IREANSIIITPGYGLCAAKA QYPIADLVKMLTEQGKKVRF GIHPVAGRMPGQLNVLLAEA GVPYDIVLEMDEINHDFPDT DLVLVIGANDTVNSAAQEDP NSIIAGMPVLEVWKSKQVIV MKRSLGVGYAAVDNPIFYKP NTAMLLGDAKKTCDALQAKV RESYQK |
| Tissue Specificity | Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues. |
| Function | The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland. |
| Protein Name | Nad(P Transhydrogenase - MitochondrialNicotinamide Nucleotide TranshydrogenasePyridine Nucleotide Transhydrogenase |
| Database Links | Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nad(P Transhydrogenase - Mitochondrial antibodyAnti-Nicotinamide Nucleotide Transhydrogenase antibodyAnti-Pyridine Nucleotide Transhydrogenase antibodyAnti-NNT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
