| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NNT |
| Gene ID: | 23530 |
| Uniprot ID: | NNTM_HUMAN |
| Immunogen Region: | 881-1086 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 881-1086 of human NNT (NP_036475.3). |
| Immunogen Sequence: | NRSLANVILGGYGTTSTAGG KPMEISGTHTEINLDNAIDM IREANSIIITPGYGLCAAKA QYPIADLVKMLTEQGKKVRF GIHPVAGRMPGQLNVLLAEA GVPYDIVLEMDEINHDFPDT DLVLVIGANDTVNSAAQEDP NSIIAGMPVLEVWKSKQVIV MKRSLGVGYAAVDNPIFYKP NTAMLLGDAKKTCDALQAKV RESYQK |
| Tissue Specificity | Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues. |
| Function | The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland. |
| Protein Name | Nad(P Transhydrogenase - MitochondrialNicotinamide Nucleotide TranshydrogenasePyridine Nucleotide Transhydrogenase |
| Database Links | Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nad(P Transhydrogenase - Mitochondrial antibodyAnti-Nicotinamide Nucleotide Transhydrogenase antibodyAnti-Pyridine Nucleotide Transhydrogenase antibodyAnti-NNT antibody |
Information sourced from Uniprot.org