| Tissue Specificity | Heart, gut, kidney, liver and placenta. |
| Function | Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle. |
| Protein Name | Glycylpeptide N-Tetradecanoyltransferase 1Myristoyl-Coa -Protein N-Myristoyltransferase 1Hsnmt1Nmt 1Type I N-MyristoyltransferasePeptide N-Myristoyltransferase 1Protein-Lysine Myristoyltransferase Nmt1 |
| Database Links | Reactome: R-HSA-162599Reactome: R-HSA-2514859Reactome: R-HSA-75108 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinCopurifies With Ribosomes |
| Alternative Antibody Names | Anti-Glycylpeptide N-Tetradecanoyltransferase 1 antibodyAnti-Myristoyl-Coa -Protein N-Myristoyltransferase 1 antibodyAnti-Hsnmt1 antibodyAnti-Nmt 1 antibodyAnti-Type I N-Myristoyltransferase antibodyAnti-Peptide N-Myristoyltransferase 1 antibodyAnti-Protein-Lysine Myristoyltransferase Nmt1 antibodyAnti-NMT1 antibodyAnti-NMT antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and ABCF2 knockout (KO) 293T cells, using [KO Validated] ABCF2 Rabbit polyclonal antibody (STJ11100826) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89762/358237/STJ11100826_1__74130.1713122569.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ABCF2 knockout (KO) 293T cells, using [KO Validated] ABCF2 Rabbit polyclonal antibody (STJ11100826) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.")
