Anti-NME7 antibody [SAA1925] (STJA0020353)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Nucleoside Diphosphate Kinase Homolog 7 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1925 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | NME7 |
| Gene ID | 29922 |
| Uniprot ID | NDK7_HUMAN |
Additional Info
| Post Translational Modifications | Undergoes autophosphorylation. |
| Function | Possesses an intrinsic kinase activity. Displays 3'-5' exonuclease activity with a preference for single-stranded DNA. Does not seem to have nucleoside diphosphate kinase activity. Functional component of the gamma-tubulin ring complex, implicated in the regulation of the microtubule-nucleating activity of the gamma-tubulin ring complex in centrosomes, in a kinase activity-dependent manner. Part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. |
| Protein Name | Nucleoside Diphosphate Kinase Homolog 7Ndk 7Ndp Kinase Homolog 73'-5' Exonuclease Nme7Protein Kinase Nme7Nm23-H7 |
| Database Links | Reactome: R-HSA-380270Reactome: R-HSA-380320 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeNucleusSpindleCilium AxonemeFlagellum AxonemeCell ProjectionCiliumLocalizes To Centrosomes Through Its Assembly Into Gamma-Tubulin Ring ComplexThe Centrosomal Content Of Nme7 Varies During The Cell CycleBeing Highest In Mitosis And Lowest In Early G1 |
| Alternative Antibody Names | Anti-Nucleoside Diphosphate Kinase Homolog 7 antibodyAnti-Ndk 7 antibodyAnti-Ndp Kinase Homolog 7 antibodyAnti-3'-5' Exonuclease Nme7 antibodyAnti-Protein Kinase Nme7 antibodyAnti-Nm23-H7 antibodyAnti-NME7 antibody |
Information sourced from Uniprot.org