| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NLRC5 |
| Gene ID: | 84166 |
| Uniprot ID: | NLRC5_HUMAN |
| Immunogen Region: | 1-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human NLRC5 (NP_115582.4). |
| Immunogen Sequence: | MDPVGLQLGNKNLWSCLVRL LTKDPEWLNAKMKFFLPNTD LDSRNETLDPEQRVILQLNK LHVQGSDTWQSFIHCVCMQL EVPLDLEVLLLSTFGYDDGF TSQLGAEGKSQPESQLHHGL KRPHQSCGSSPRRKQCKKQQ LELAKKYLQLLRTSAQQRYR SQIPGSGQPHAFHQVYVPPI LRRATASLDTPEGAIMGDVK VEDGADVSISDLFNTRVNKG PRVTVLLGKAGMGKTTLAH |
| Tissue Specificity | Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate. |
| Function | Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. |
| Protein Name | Protein Nlrc5Caterpiller Protein 16.1Clr16.1Nucleotide-Binding Oligomerization Domain Protein 27Nucleotide-Binding Oligomerization Domain Protein 4 |
| Database Links | Reactome: R-HSA-168928Reactome: R-HSA-936440Reactome: R-HSA-9758274 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein Nlrc5 antibodyAnti-Caterpiller Protein 16.1 antibodyAnti-Clr16.1 antibodyAnti-Nucleotide-Binding Oligomerization Domain Protein 27 antibodyAnti-Nucleotide-Binding Oligomerization Domain Protein 4 antibodyAnti-NLRC5 antibodyAnti-NOD27 antibodyAnti-NOD4 antibody |
Information sourced from Uniprot.org