Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NKX6-1 (1-100) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:100-1:500IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NKX6-1 |
Gene ID: |
4825 |
Uniprot ID: |
NKX61_HUMAN |
Immunogen Region: |
1-100 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NKX6-1 (NP_006159.2). |
Immunogen Sequence: |
MLAVGAMEGTRQSAFLLSSP PLAALHSMAEMKTPLYPAAY PPLPAGPPSSSSSSSSSSSP SPPLGTHNPGGLKPPATGGL SSLGSPPQQLSAATPHGIND |
Tissue Specificity | Pancreatic beta cells. |
Function | Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals. |
Protein Name | Homeobox Protein Nkx-6.1Homeobox Protein Nk-6 Homolog A |
Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210747 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Homeobox Protein Nkx-6.1 antibodyAnti-Homeobox Protein Nk-6 Homolog A antibodyAnti-NKX6-1 antibodyAnti-NKX6A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance