NKX31 antibody immunohistochemistry human prostate tissue STJA0033365

Anti-NKX3.1 antibody [ZN195] (STJA0033365)

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STJA0033365
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Short Description :Mouse monoclonal anti-NKX3.1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :ZN195
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:0.5-1.0 mg/mL
Purification:Affinity Chromatography
Dilution Range:IHC 1:50-1:100
Formulation:PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:NKX3-1
Gene ID:4824
Uniprot ID:NKX31_HUMAN
Immunogen:Full length human recombinant protein of human NKX3-1 (NP_006158) produced in E.coli.
Tissue Specificity Highly expressed in the prostate and, at a lower level, in the testis.
Post Translational Modifications Ubiquitinated by TOPORS.monoubiquitinated at several residues and also polyubiquitinated on single residues.
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGTAG-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Protein Name Homeobox Protein Nkx-3.1
Homeobox Protein Nk-3 Homolog A
Database Links
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Nkx-3.1 antibody
Anti-Homeobox Protein Nk-3 Homolog A antibody
Anti-NKX3-1 antibody
Anti-NKX3.1 antibody
Anti-NKX3A antibody

Information sourced from Uniprot.org

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