• LnCap whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-NKX3. 1 (ABT267) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: LnCapPredicted band size: 26kDaObserved band size: 32kDa
  • Human prostate tissue was stained with Anti-NKX3. 1 (ABT267) Antibody
  • Human prostatic adenocarcinoma tissue was stained with Anti-NKX3. 1 (ABT267) Antibody
  • Human salivary gland tissue was stained with Anti-NKX3. 1 (ABT267) Antibody

Anti-NKX3-1 antibody (1-100 aa) [ABT267] (STJ197243)

SKU:
STJ197243

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Homeobox protein Nkx-3.1 (1-100 aa) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality: Monoclonal
Clone ID: ABT267
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:200-400
WB 1:200-1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NKX3-1
Gene ID: 4824
Uniprot ID: NKX31_HUMAN
Immunogen Region: 1-100 aa
Specificity: The antibody can specifically recognize human NKX3.1 protein.
Immunogen: Synthesized peptide derived from the human NKX3.1 at the amino acid range 1-100
Post Translational Modifications Ubiquitinated by TOPORS.monoubiquitinated at several residues and also polyubiquitinated on single residues.
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGTAG-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Protein Name Homeobox Protein Nkx-3.1
Homeobox Protein Nk-3 Homolog A
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Nkx-3.1 antibody
Anti-Homeobox Protein Nk-3 Homolog A antibody
Anti-NKX3-1 antibody
Anti-NKX3.1 antibody
Anti-NKX3A antibody

Information sourced from Uniprot.org

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