Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-NKX2.2 (1-119aa) is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | ZM14 |
Conjugation: | Unconjugated |
Isotype: | IgG1/Kappa |
Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
Purification: | Affinity purified |
Dilution Range: | 1:100‐200 |
Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Gene Symbol: | NKX2-2 |
Gene ID: | 4821 |
Uniprot ID: | NKX22_HUMAN |
Immunogen Region: | 1-119aa |
Specificity: | Positive control: Ewing's sarcoma |
Immunogen: | Human recombinant NKX2.2 protein fragment (aa 1-119) |
Function | Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas. May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter. |
Protein Name | Homeobox Protein Nkx-2.2Homeobox Protein Nk-2 Homolog B |
Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210746 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Homeobox Protein Nkx-2.2 antibodyAnti-Homeobox Protein Nk-2 Homolog B antibodyAnti-NKX2-2 antibodyAnti-NKX2.2 antibodyAnti-NKX2B antibody |
Information sourced from Uniprot.org