• Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-NKIRAS2 antibody (STJ191911)

SKU:
STJ191911

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NF-kappa-B inhibitor-interacting Ras-like protein 2 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NKIRAS2
Gene ID: 28511
Uniprot ID: KBRS2_HUMAN
Specificity: KBRS2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Protein Name Nf-Kappa-B Inhibitor-Interacting Ras-Like Protein 2
I-Kappa-B-Interacting Ras-Like Protein 2
Kappa B-Ras Protein 2
Kappab-Ras2
Database Links Reactome: R-HSA-1810476
Reactome: R-HSA-445989
Reactome: R-HSA-933542
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Nf-Kappa-B Inhibitor-Interacting Ras-Like Protein 2 antibody
Anti-I-Kappa-B-Interacting Ras-Like Protein 2 antibody
Anti-Kappa B-Ras Protein 2 antibody
Anti-Kappab-Ras2 antibody
Anti-NKIRAS2 antibody
Anti-KBRAS2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance