| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein naked cuticle homolog 2 (311-361 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NKD2 |
| Gene ID: |
85409 |
| Uniprot ID: |
NKD2_HUMAN |
| Immunogen Region: |
311-361 aa |
| Specificity: |
This antibody detects endogenous levels of NKD2 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human NKD2 at the amino acid range 311-361 |
| Post Translational Modifications | Ubiquitinated, leading to rapid proteasomal degradation. Interaction with TGFA interferes with RNF25 binding and protects against ubiquitination mediated by RNF25. |
| Function | Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells. |
| Protein Name | Protein Naked Cuticle Homolog 2Naked-2Hnkd2 |
| Cellular Localisation | Cell MembraneCytoplasmCytoplasmic Vesicle |
| Alternative Antibody Names | Anti-Protein Naked Cuticle Homolog 2 antibodyAnti-Naked-2 antibodyAnti-Hnkd2 antibodyAnti-NKD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
