• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-NICOL1 antibody (24-74 aa) (STJ196219)

SKU:
STJ196219

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NELL2-interacting cell ontogeny regulator 1 (24-74 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NICOL1
Uniprot ID: NICOL_HUMAN
Immunogen Region: 24-74 aa
Specificity: This antibody detects endogenous levels of CD048 at Human/Mouse
Immunogen: Synthesized peptide derived from the human CD048 at the amino acid range 24-74
Function mRNA-binding protein which interacts with a range of target mRNAs including SERPINE1, ACTA2, CCN2 and COL4A1 and may promote extracellular matrix production. Binds to the 3'-UTR of SERPINE1 mRNA and stabilizes the mRNA, possibly by competing for binding with SERBP1 and preventing SERBP1-mediated mRNA degradation. Also binds to the 3'-UTR of ACTA2. Testis-derived lumicrine factor that triggers epididymal differentiation and sperm maturation.
Protein Name Nell2-Interacting Cell Ontogeny Regulator 1
Nell2-Interacting Cofactor For Lumicrine Signaling
Nicol
Cellular Localisation Secreted
Cytoplasm
Perinuclear Region
Detected In The Perinuclear Region Of Fibroblasts
Alternative Antibody Names Anti-Nell2-Interacting Cell Ontogeny Regulator 1 antibody
Anti-Nell2-Interacting Cofactor For Lumicrine Signaling antibody
Anti-Nicol antibody
Anti-NICOL1 antibody
Anti-C4orf48 antibody

Information sourced from Uniprot.org

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