Anti-NFX1 antibody (80-160 aa) (STJ191544)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 80-160
STJ191544
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General Information

Short DescriptionRabbit polyclonal anti-Transcriptional repressor NF-X1 (80-160 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolNFX1
Gene ID4799
Uniprot IDNFX1_HUMAN
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 80-160
Immunogen Region80-160 aa
SpecificityNFX1 Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Function Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
Protein Name Transcriptional Repressor Nf-X1
Nuclear Transcription Factor - X Box-Binding Protein 1
Database Links
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcriptional Repressor Nf-X1 antibody
Anti-Nuclear Transcription Factor - X Box-Binding Protein 1 antibody
Anti-NFX1 antibody
Anti-NFX2 antibody

Information sourced from Uniprot.org

Citations

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