| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nuclear factor related to kappa-B-binding protein (463-512) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-p 1:50-300 ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NFRKB |
| Gene ID: | 4798 |
| Uniprot ID: | NFRKB_HUMAN |
| Immunogen Region: | 463-512 |
| Specificity: | NFR Kappa B Polyclonal Antibody detects endogenous levels of NFR Kappa B protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NFRKB. AA range:463-512 |
| Tissue Specificity | Expressed in thymus, brain, testes, spleen and liver. |
| Function | Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex. |
| Protein Name | Nuclear Factor Related To Kappa-B-Binding Protein Dna-Binding Protein R Kappa-B Ino80 Complex Subunit G |
| Database Links | Reactome: R-HSA-5689603 Reactome: R-HSA-5696394 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Factor Related To Kappa-B-Binding Protein antibody Anti-Dna-Binding Protein R Kappa-B antibody Anti-Ino80 Complex Subunit G antibody Anti-NFRKB antibody Anti-INO80G antibody |
Information sourced from Uniprot.org