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Anti-NF1 antibody (1551-1600) (STJ94430)

Western blot analysis of lysates from HepG2 cells, using NF1 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of HepG2 cells using Neurofibromin Polyclonal Antibody
Immunofluorescence analysis of HepG2 cells, using NF1 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of various cells using Neurofibromin Polyclonal Antibody

Anti-NF1 antibody (1551-1600) (STJ94430)

SKU:

STJ94430

£48.00 - £252.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Neurofibromin (1551-1600) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 IHC-p 1:50-300
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	NF1
Gene ID:	4763
Uniprot ID:	NF1_HUMAN
Immunogen Region:	1551-1600
Specificity:	Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600

Tissue Specificity	Detected in brain, peripheral nerve, lung, colon and muscle.
Post Translational Modifications	Ubiquitinated by RNF7/RBX2, leading to its degradation.
Function	Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.
Protein Name	Neurofibromin Neurofibromatosis-Related Protein Nf-1 Cleaved Into - Neurofibromin Truncated
Database Links	Reactome: R-HSA-5658442 Reactome: R-HSA-6802953
Cellular Localisation	Nucleus Nucleolus Cell Membrane
Alternative Antibody Names	Anti-Neurofibromin antibody Anti-Neurofibromatosis-Related Protein Nf-1 Cleaved Into - Neurofibromin Truncated antibody Anti-NF1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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