| Short Description : | Mouse monoclonal anti-Neurturin for use in ELISA, WB and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB/IF |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 1B11 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | Protein G purification |
| Dilution Range: | WB 0.2 to 1 µg/ml; ELISA 0.05 to 0.1 µg/ml; IF 5 to 10 µg/ml Monoclonal antibody working titer has to be established practically for each particular antigen and assay format |
| Formulation: | PBS pH 7.4, with 0.1% sodium azide |
| Storage Instruction: | Store at-20 or-70 °C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles as product degradation may result |
| Gene Symbol: | NRTN |
| Gene ID: | 4902 |
| Uniprot ID: | NRTN_HUMAN |
| Immunogen: | Recombinant human NRTN protein produced using CHO-based proprietary suspension cell line. Protein was purified from the cell culture supernatant. human Neurturin |
| Specificity: | Human NRTN |
| Function | Growth factor that supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Involved in the development of the neural crest. Might control the size of non-neuronal cell population such as haemopoietic cells. Acts by binding to its coreceptor, GFRA2, leading to autophosphorylation and activation of the RET receptor. Heparan sulfate-binding is required for signaling. |
| Protein Name | Neurturin |
| Database Links | Reactome: R-HSA-419037Reactome: R-HSA-5673001Reactome: R-HSA-8853659 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Neurturin antibodyAnti-NRTN antibody |
Information sourced from Uniprot.org
