| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NEUROG1 |
| Gene ID: | 4762 |
| Uniprot ID: | NGN1_HUMAN |
| Immunogen Region: | 1-237 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human NEUROG1 (Q92886). |
| Immunogen Sequence: | MPARLETCISDLDCASSSGS DLSGFLTDEEDCARLQQAAS ASGPPAPARRGAPNISRASE VPGAQDDEQERRRRRGRTRV RSEALLHSLRRSRRVKANDR ERNRMHNLNAALDALRSVLP SFPDDTKLTKIETLRFAYNY IWALAETLRLADQGLPGGGA RERLLPPQCVPCLPGPPSPA SDAESWGSGAAAASPLSDPS SPAASEDFTYRPGDPVFSFP SLPKDLLHTTPCFIPYH |
| Tissue Specificity | Expression restricted to the embryonic nervous system. |
| Function | Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. |
| Protein Name | Neurogenin-1Ngn-1Class A Basic Helix-Loop-Helix Protein 6Bhlha6Neurogenic Basic-Helix-Loop-Helix ProteinNeurogenic Differentiation Factor 3Neurod3 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Neurogenin-1 antibodyAnti-Ngn-1 antibodyAnti-Class A Basic Helix-Loop-Helix Protein 6 antibodyAnti-Bhlha6 antibodyAnti-Neurogenic Basic-Helix-Loop-Helix Protein antibodyAnti-Neurogenic Differentiation Factor 3 antibodyAnti-Neurod3 antibodyAnti-NEUROG1 antibodyAnti-BHLHA6 antibodyAnti-NEUROD3 antibodyAnti-NGN antibodyAnti-NGN1 antibody |
Information sourced from Uniprot.org
