| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Mouse/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Neurobeachin (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.IHC: In paraffin embedded Human Cerebral Cortex shows textured cytoplasm staining in the neuronal cell bodies. Recommended concentration: 5-10µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | NBEA |
| Gene ID: | 26960 |
| Uniprot ID: | NBEA_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_056493.3; NP_001191126.1 |
| Specificity: | This antibody is expected to recognise isoform 1 (NP_056493.3) and isoform 2 (NP_001191126.1). |
| Immunogen Sequence: | DFNRWHYEHQNRY |
| Function | Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. |
| Protein Name | NeurobeachinLysosomal-Trafficking Regulator 2Protein Bcl8b |
| Database Links | Reactome: R-HSA-112314Reactome: R-HSA-163615Reactome: R-HSA-2122947Reactome: R-HSA-9609736 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Neurobeachin antibodyAnti-Lysosomal-Trafficking Regulator 2 antibodyAnti-Protein Bcl8b antibodyAnti-NBEA antibodyAnti-BCL8B antibodyAnti-KIAA1544 antibodyAnti-LYST2 antibody |
Information sourced from Uniprot.org