Anti-Neural Cell Adhesion Molecule antibody [RNL-1] (STJ16100890)

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STJ16100890-1
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Short Description :Mouse monoclonal anti-Neural Cell Adhesion Molecule for use in IHC-F and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-F/WB
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RNL-1
Isotype:IgG1
Conjugation:Unconjugated
Dilution Range:IHC-F 1:10-1:20
WB
Formulation:Contains 0.09% sodium azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Gene Symbol:NCAM1
Gene ID:4684
Uniprot ID:NCAM1_HUMAN
Immunogen:Cytoskeletal preparation of human epidermis
Post Translational Modifications Polysialylated at Asn-459 and Asn-488 by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans.
Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus.
Protein Name Neural Cell Adhesion Molecule 1
N-Cam-1
Ncam-1
Cd Antigen Cd56
Database Links Reactome: R-HSA-3000178
Reactome: R-HSA-375165
Reactome: R-HSA-419037
Reactome: R-HSA-445144
Reactome: R-HSA-5673001
Reactome: R-HSA-877300
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cell Membrane
Isoform 3: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 4: Cell Membrane
Isoform 5: Secreted
Isoform 6: Secreted
Alternative Antibody Names Anti-Neural Cell Adhesion Molecule 1 antibody
Anti-N-Cam-1 antibody
Anti-Ncam-1 antibody
Anti-Cd Antigen Cd56 antibody
Anti-NCAM1 antibody
Anti-NCAM antibody

Information sourced from Uniprot.org

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