| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Neudesin/NENF (Internal) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx 45kDa band in Human Brain (Cerebellum) lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
NENF |
| Gene ID: |
29937 |
| Uniprot ID: |
NENF_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_037481.1 |
| Immunogen Sequence: |
NEDGSPNLDFKP |
| Function | Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance. |
| Protein Name | NeudesinCell Immortalization-Related Protein 2Neuron-Derived Neurotrophic FactorProtein Gig47Secreted Protein Of Unknown FunctionSpuf Protein |
| Cellular Localisation | SecretedExtracellular SpaceMitochondrionEndoplasmic ReticulumLocalized To Mitochondria And Endoplasmic Reticulum By Pink1 And Park7 |
| Alternative Antibody Names | Anti-Neudesin antibodyAnti-Cell Immortalization-Related Protein 2 antibodyAnti-Neuron-Derived Neurotrophic Factor antibodyAnti-Protein Gig47 antibodyAnti-Secreted Protein Of Unknown Function antibodyAnti-Spuf Protein antibodyAnti-NENF antibodyAnti-CIR2 antibodyAnti-SPUF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
