Anti-NEU1/Sialidase-1 antibody [1A040] (STJA0019916)

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STJA0019916
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Sialidase-1 is suitable for use in ELISA and Western Blot research applications.
Clonality : Monoclonal
Clone ID : 1A040
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: NEU1
Gene ID: 4758
Uniprot ID: NEUR1_HUMAN
Immunogen: Recombinant Human NEU1/Sialidase-1 protein
Post Translational Modifications N-glycosylated. Phosphorylation of tyrosine within the internalization signal results in inhibition of sialidase internalization and blockage on the plasma membrane.
Function Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage.
Protein Name Sialidase-1
Acetylneuraminyl Hydrolase
G9 Sialidase
Lysosomal Sialidase
N-Acetyl-Alpha-Neuraminidase 1
Database Links Reactome: R-HSA-4085001
Reactome: R-HSA-4341670
Reactome: R-HSA-6798695
Reactome: R-HSA-9840310
Cellular Localisation Lysosome Membrane
Peripheral Membrane Protein
Lumenal Side
Lysosome Lumen
Cell Membrane
Cytoplasmic Vesicle
Lysosome
Localized Not Only On The Inner Side Of The Lysosomal Membrane And In The Lysosomal Lumen
But Also On The Plasma Membrane And In Intracellular Vesicles
Alternative Antibody Names Anti-Sialidase-1 antibody
Anti-Acetylneuraminyl Hydrolase antibody
Anti-G9 Sialidase antibody
Anti-Lysosomal Sialidase antibody
Anti-N-Acetyl-Alpha-Neuraminidase 1 antibody
Anti-NEU1 antibody
Anti-NANH antibody

Information sourced from Uniprot.org

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