Anti-NENF antibody (120-170 aa) (STJ13101496)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 120-170 of human NENF conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-NENF (120-170 aa) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | NENF |
| Gene ID | 29937 |
| Uniprot ID | NENF_HUMAN |
| Immunogen | A synthetic peptide from aa region 120-170 of human NENF conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 120-170 aa |
| Specificity | Specific for NENF. |
Additional Info
| Function | Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Also acts as an anorexigenic neurotrophic factor that contributes to energy balance. |
| Protein Name | NeudesinCell Immortalization-Related Protein 2Neuron-Derived Neurotrophic FactorProtein Gig47Secreted Protein Of Unknown FunctionSpuf Protein |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceMitochondrionEndoplasmic ReticulumLocalized To Mitochondria And Endoplasmic Reticulum By Pink1 And Park7 |
| Alternative Antibody Names | Anti-Neudesin antibodyAnti-Cell Immortalization-Related Protein 2 antibodyAnti-Neuron-Derived Neurotrophic Factor antibodyAnti-Protein Gig47 antibodyAnti-Secreted Protein Of Unknown Function antibodyAnti-Spuf Protein antibodyAnti-NENF antibodyAnti-CIR2 antibodyAnti-SPUF antibody |
Information sourced from Uniprot.org