| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NENF (120-170 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
NENF |
| Gene ID: |
29937 |
| Uniprot ID: |
NENF_HUMAN |
| Immunogen Region: |
120-170 aa |
| Specificity: |
Specific for NENF. |
| Immunogen: |
A synthetic peptide from aa region 120-170 of human NENF conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance. |
| Protein Name | NeudesinCell Immortalization-Related Protein 2Neuron-Derived Neurotrophic FactorProtein Gig47Secreted Protein Of Unknown FunctionSpuf Protein |
| Cellular Localisation | SecretedExtracellular SpaceMitochondrionEndoplasmic ReticulumLocalized To Mitochondria And Endoplasmic Reticulum By Pink1 And Park7 |
| Alternative Antibody Names | Anti-Neudesin antibodyAnti-Cell Immortalization-Related Protein 2 antibodyAnti-Neuron-Derived Neurotrophic Factor antibodyAnti-Protein Gig47 antibodyAnti-Secreted Protein Of Unknown Function antibodyAnti-Spuf Protein antibodyAnti-NENF antibodyAnti-CIR2 antibodyAnti-SPUF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
